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Article: h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data.(Methodology article)
- Article from:
- BMC Bioinformatics
- Article date:
- December 20, 2007
- Author:
CopyrightCOPYRIGHT 2007 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Yvonne E Pittelkow (corresponding author) [1]; Susan R Wilson (corresponding author) [1]
Background
In gene expression (or transcript profiling) experiments, gene expression is often compared under different experimental perturbations, such as between different genotypes, cell lines, diseased and healthy subjects or under different treatment conditions. Another, complementary approach, which is useful for understanding the dynamics of altered gene expression, is via time course data, where gene expression is measured at different time intervals, usually under the same experimental conditions.
Genes with similar expression profiles, ...
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