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Pioglitazone may lower cardiovascular risk in CKD patients.(Cardiovascular Medicine)(Clinical report)

Treatment with pioglitazone might help lower the risk of cardiovascular events in patients with chronic kidney disease, the results of a large study suggest.

"CKD, as defined by a glomerular filtration rate of less than 60 mL/min per 1.73 [m.sup.2], is an independent risk factor for major adverse cardiovascular events and death in this high-risk population," the researchers said. "Our data suggest patients with diabetes and high risk identified by CKD can be treated effectively with pioglitazone."

The study, by Dr. Christian A. Schneider of the University of Cologne (Germany), and his associates, was traded by Takeda Pharmaceutical Co., which makes Actos ...

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