Article: Hormones, Heart, and Cancer; The latest findings from the Women's Health Initiative should be interpreted with caution.(estrogen-progestin therapy)

Byline: Bernadine Healy M.D.

How women use postmenopausal hormones was forever changed about six years ago by the Women's Health Initiative. Rather than seeing hormone replacement as the answer to all female problems of middle age and beyond, doctors now typically prescribe combined estrogen-progestin therapy case by case, in the lowest possible dose for the shortest duration of time, and mainly in that subset of women who cannot otherwise control the debilitating symptoms of menopause. The practice shift came almost overnight, with the WHI findings that combined hormones appear to raise the risk of invasive breast cancer, and increase, at least a little--not decrease--the ...

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