Article: Use of botulinum toxin type A in children with cerebral palsy.(Update)

Key Words: Cerebral palsy, Drugs, Spasticity.

Cerebral palsy is one of the most common causes of activity limitation in children. The central nervous system (CNS) lesion causing the disorder of posture and movement is nonprogressive, but the manifestations of the lesion may change over time. Children with cerebral palsy may display a range of movement disorders, alone or in combination, including dystonia, athetosis, ataxia, and spasticity. (1) Spasticity is a complex phenomenon and has been defined as "a motor disorder characterized by a velocity-dependent increase in tonic stretch reflexes (muscle tone) with exaggerated tendon jerks, resulting from ...

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