Article: Transmission of equine influenza virus to English foxhounds.(DISPATCHES)

We retrospectively demonstrated that an outbreak of severe respiratory disease in a pack of English foxhounds in the United Kingdom in September 2002 was caused by an equine influenza A virus (H3N8). We also demonstrated that canine respiratory tissue possesses the relevant receptors for infection with equine influenza virus.

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Influenza A viruses are divided into subtypes according to the serologic reactivity of the surface glycoproteins hemagglutinin (H1-H16) and neuraminidase (N1-N9). Aquatic birds are regarded as the natural reservoir for influenza A viruses; a few mammalian hosts are infected by a limited number of virus subtypes. The first ...

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