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Gr-3. Orientation of structures.(GRAPHICAL REPRESENTATION STANDARDS FOR CHEMICAL STRUCTURE DIAGRAMS **)

When considering the guidelines to follow for the orientation of chemical structures, perhaps the most important thing to keep in mind is that, as far as chemical meaning is concerned, they do not matter. With a single exception in the case of Fischer projections [17,18], simple rotation of a chemical structure within the plane of the diagram will never affect its chemical meaning. Flipping a portion of a structure requires a corresponding adjustment of stereobonds (solid wedged bonds must be changed to hashed wedged bonds, etc.), but changes nothing otherwise. In terms of chemical meaning, the orientation of structures is irrelevant.

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