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Article: SSRI use may increase risk of upper GI bleeding.(Across Specialties)
- Article from:
- Skin & Allergy News
- Article date:
- March 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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A new analysis of data from observational studies and case reports as confirmed that the use of selective serotonin reuptake inhibitors is associated with an increased risk of upper gastrointestinal hemorrhage, particularly in patients also taking NSAIDs.
Previous studies have suggested that SSRIs are linked to abnormal bleeding, including that of the upper GI tract. However, the magnitude of the risk has not been known, particularly when these drugs are used with other medications associated with bleeding, according to the study (Aliment. Pharmacol. Ther. 2008;27:31-40).
In a teleoanalysis that included one cohort study, three case-control studies, and ...