Article: Aspirin resistance attributed to noncompliance.(Cardiovascular Medicine)

ATLANTA -- Noncompliance is the main cause of aspirin resistance, according to investigators who studied aspirin response in 230 people, most of whom had a history of myocardial infarction.

The study initially classified up to 30% of the participants as aspirin resistant, but in the end, only 4% of 185 people in whom aspirin response was measured met a conservative definition of aspirin resistance. These seven patients were determined to have a low response to aspirin. One person violated the study's protocols by taking a nonaspirin nonsteroidal anti-inflammatory drug (NANSAID) that would have interfered with aspirin's effects.

Among participants who ...

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