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Article: Aspirin resistance attributed to noncompliance.(Cardiovascular Medicine)
- Article from:
- Family Practice News
- Article date:
- March 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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ATLANTA -- Noncompliance is the main cause of aspirin resistance, according to investigators who studied aspirin response in 230 people, most of whom had a history of myocardial infarction.
The study initially classified up to 30% of the participants as aspirin resistant, but in the end, only 4% of 185 people in whom aspirin response was measured met a conservative definition of aspirin resistance. These seven patients were determined to have a low response to aspirin. One person violated the study's protocols by taking a nonaspirin nonsteroidal anti-inflammatory drug (NANSAID) that would have interfered with aspirin's effects.
Among participants who ...