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Article: Increase in collagen turnover induced by intradermal injection of carbon dioxide in rats.
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- March 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Introduction
Human tissue changes with age. In the skin, these modifications are more easily recognized. (1,2) The modifications to the collagen and elastin system cause wrinkles, atrophy, grooves, ptosis, and laxity. These are the most evident signs of old skin, (3-6) which can result in significant psychological problems for individuals. There is increasing interest in therapeutic resources for solving such problems. (7) For this reason, the morphological and structural changes to the dermis related to aging are constantly being studied.
Many authors have shown that there are beneficial effects from subcutaneous carbon dioxide (C[O.sub.2]) therapy for ...