Article: Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies.

BETHESDA, Md., April 14 /PRNewswire-FirstCall/ -- Micromet, Inc. , a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, presented at the annual meeting of the American Association for Cancer Research (AACR) in San Diego, CA, data showing that commercial anti-cancer antibodies trastuzumab (Herceptin(R); Genentech, Roche), cetuximab (Erbitux(R); Bristol-Myers Squibb, Imclone, Merck Serono), and panitumumab (Vectibix(R); Amgen) can be converted to highly potent BiTE(R) antibodies (1). Likewise, the anti-IgE antibody omalizumab (Xolair(R); Genentech, Novartis) for the treatment of asthma can ...

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