WAIKOLOA, HAWAII -- DNA micro array analysis of melanomas has identified several key genes whose over or underexpression provides novel independent prognostic markers for melanoma outcome.
"We think that markers like these could be used (a) to understand melanoma biology, and (b), to select patients for appropriate management," Dr. Mohammed Kashani-Sabet said at the annual Hawaii dermatology seminar sponsored by Skin Disease Education Foundation.
"The molecular signature of metastasis can be present in very early melanoma," stressed Dr. Kashani-Sabet of the University of California, San Francisco, Comprehensive Cancer Center. Two of the best-studied of these novel ...