CHICAGO -- Spironolactone and statins added to ACE inhibitors and angiotensin II receptor blockers further reduces proteinuria and the rate of chronic kidney disease progression, a study has found.
Prior research by the same investigators showed that treatment with statins and aldosterone antagonists also may independently reduce proteinuria and the progression of chronic kidney disease (Kidney Int. 2006;70:2116-23).
Based on their work, lead researcher Dr. Roberto Bigazzi, of the nephrology unit at Spedali Riuniti, Livorno, Italy, and his associates concluded that "the optimal treatment of chronic kidney disease requires an integrated approach of several pathogenic ...