Pharmacokinetics describes the time course of the drug concentration following administration of a specific dosage regimen. An understanding of pharmacokinetic principles will assist the clinician in designing an individualized dosage regimen that achieves the desired drug concentration.
The clinical use of drugs is becoming increasingly more complex. An understanding of the relationship between the administered dose of a drug, the resulting concentration, and its biologic effect will facilitate the rational use of drug therapy. The study of pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body) is the basis of pharmacotherapy ...