The Problem
You have a patient with schizophrenia who is considering treatment with an antipsychotic medication. After reviewing the potential irreversibility of tardive dyskinesia, the patient questions you about antipsychotic-induced diabetes.
The Question
Is antipsychotic-induced diabetes reversible?
The Analysis
We first searched the Cochrane Database of Systematic Reviews (www.cochrane.org) and found no reviews on this topic. We then searched Medline, combining "antipsychotic" and "diabetes or hyperglycemia" and "revers$."
The Evidence
To help us answer this question, we first turned to a review article by Dr. John W. Newcomer and Dr. Dan ...