Optimal design via curve fitting of Monte Carlo experiments.

Numerical methods for stochastic optimization focusing on Bayesian design are proposed. The approach is based on transforming a complex numerical problem into a simpler statistical problem. The key to the solution strategy is a four-step sequence of simulating, modeling, smoothing and optimizing. The proposed algorithm relies on a curve-fitting procedure.

This article explores numerical methods for stochastic optimization, with special attention to Bayesian design problems. A common and challenging situation occurs when the objective function (in Bayesian applications, the expected utility) is very expensive to evaluate, perhaps because it requires integration over a space of very ...

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