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Clinical highlights: hyperviscosity syndrome in patients with multiple myeloma.(CLINICAL CHALLENGES)(Disease/Disorder overview)

Definition

Hyperviscosity syndrome is the term used to describe the clinical signs and symptoms related to increased blood viscosity. Hyperviscosity is defined on the basis of the relative viscosity of blood compared to water (Park et al., 2005), with normal serum viscosity level 1.8 centipoise (cp).

Incidence

Approximately 50,000 Americans have multiple myeloma, with 19,900 new diagnoses in 2007 (Jemal et al., 2007). The disease is more common in men than women, and more common in African Americans than other ethnic groups. Hyperviscosity syndrome is a rare complication of multiple myeloma that occurs in about 2%-6% of patients, most frequently in immunoglobulin ...

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