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Article: TPA fails in women with metabolic syndrome: the effect may be caused by defective endogenous fibrinolysis, a hallmark of metabolic syndrome.(Clinical Rounds)(Clinical report)
- Article from:
- Family Practice News
- Article date:
- May 1, 2008
- Author:
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NEW ORLEANS -- The detrimental effect of metabolic syndrome on recanalization after intravenous thrombolytic treatment of acute ischemic stroke appears to be more pronounced in women than in men, according to the results of a prospective study.
Among patients with metabolic syndrome, women were more than three times as likely as were men to have incomplete recanalization of an acute occlusion of the middle cerebral artery (MCA) after the administration of intravenous tissue plasminogen activator (TPA), Dr. Juan F. Arenillas reported at the International Stroke Conference 2008.
At the same conference last year, Dr. Arenillas of the stroke unit in the ...