Article: TransMolecular Initiates Phase 1 Clinical Trial for Unlabeled TM601 in Recurrent Malignant Glioma.

-Initiation follows announcement of anti-angiogenic activity of the peptide-

CAMBRIDGE, Mass. -- TransMolecular, Inc., a biotechnology company focused on targeted therapies for cancer, today announced the initiation of a Phase 1 trial to test the safety, tolerability, dosing and pharmacokinetics of non-radiolabeled TM601 for the treatment of malignant glioma. The target population for the study is adult patients with progressive and/or recurrent malignant glioma who have failed first-line, standard therapy. Radiolabeled 131Iodine-TM601 is being investigated in multiple cancer types through both local and intravenous delivery, including Phase 2 studies in malignant glioma ...

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