Article: Second Phase III Study of Avastin Plus Chemotherapy Shows Improved Progression-Free Survival in Women with Advanced HER2-Negative Breast Cancer.

- Positive AVADO Results Support Efficacy and Safety of Avastin in First-Line Metastatic Breast Cancer -

CHICAGO -- Genentech, Inc. (NYSE:DNA) today announced that Avastin([R]) (bevacizumab), in combination with docetaxel chemotherapy, significantly increased the time women with metastatic breast cancer receiving first-line therapy lived without their disease advancing, as defined by the primary endpoint of progression-free survival (PFS). In this Roche-sponsored, placebo-controlled Phase III trial (AVADO), two dose levels of Avastin in combination with docetaxel chemotherapy showed a statistically significant improvement in PFS compared to docetaxel chemotherapy ...

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