Article: Oral probiotic and prevention of Pseudomonas aeruginosa infections: a randomized, double-blind, placebo-controlled pilot study in intensive care unit patients.(Research)(Clinical report)

Authors: Christiane Forestier (corresponding author) [1]; Dominique Guelon [2]; Val érie Cluytens [2]; Thierry Gillart [2]; Jacques Sirot [3]; Christophe De Champs [4]

Introduction

Hospital-acquired infections are recognized as an important determinant of outcome in patients who require intensive care unit (ICU) admission. The source of respiratory tract colonization can be exogenous, for example from the hands of health care workers or the patient's skin, but it can also be endogenous, such as from the intestine, the oropharynx and the gastric compartment, followed by retrograde contamination [1, 2, 3, 4]. Bacterial proliferation in ...

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