Optimization of Radioimmunotherapy of Renal Cell Carcinoma: Labeling of...

The Journal of Nuclear Medicine;  February 1, 2004 ;     700+ words ......injection). Maximum tumor uptake for ^sup 125^l-cG250 and ^sup 186^Re-mercaptoacetyltriglycine(MAG3)-cG250 (<20 3 %ID...growth was delayed most effectively by cG250 labeled with ^sup 177^Lu, next most effectively by ^sup 90^Y and ^sup 186^Re (which were approximately equal), and ...

Radioimmunotherapy of Non-Hodgkin's Lymphoma with ^sup 90^Y-DOTA Humanized...

The Journal of Nuclear Medicine;  December 1, 2003 ;     700+ words ......sixteen of 165 CT-confirmed lesions were visualized with ^sup 111^In-DOTA-epratuzumab. Radiation-absorbed doses to liver...significant hematologie toxicities, but doses of up to 0.370 GBq/m^sup 2^ of ^sup 90^Y-DOTA-epratuzumab were tolerated with standard support...whereas patients in group 1 tolerated ...

The Relationship between Single-Channel and Whole-Cell Conductance in the...

Biophysical Journal;  July 15, 2008 ;     700+ words ...ABSTRACT In T-type Ca^sup 2+^ channels, macroscopic I^sub Ba^ is usually smaller than I^sub Ca^, but at high Ca^sup 2+^ and Ba^sup 2+^, single-channel conductance (γ) is equal. We investigated y as a function of divalent concentration...well described by Langmuir isotherms with γ^sub ...

^sup 18^F-FLT PET for Visualization of Laryngeal Cancer: Comparison with...

The Journal of Nuclear Medicine;  February 1, 2004 ;     700+ words ......18^F-FLT (P < 0.001). TNT was 1.9 (range, 1.3-4.7) for ^sup 18^F-FDG and 1.5 (range, 1.1-3.5) for ^sup 18^F-FLT (P < 0.05). Conclusion: The numbers of laryngeal cancers detected with ^sup 18^F-FLT PET and ^sup 18^F-FDG PET were equal. In laryngeal cancer, the uptake of ^sup ...

Differential effects of voltage-dependent inactivation and local...

Biophysical Journal;  July 1, 2003 ;     700+ words ......1992) generally support the scheme, while studies of Ca^sup 2+^ sparks have added to the evidence. Because the peak of Ca^sup 2+^ release appears to reflect superposition of many synchronous sparks, the evidence that sparks are gated by Ca^sup 2+^ (Klein et al., 1996) upholds the CICR hypothesis. ...

Preclinical Safety Evaluation of ^sup 18^F-FHBG: A PET Reporter Probe for...

The Journal of Nuclear Medicine;  April 1, 2006 ;     700+ words ...9-(4-^sup 18^F-Fluoro-3-[hydroxymethyl]butyl)guanine (^sup 18^F-FHBG) is a sensitive and specific...HSV1-tk) and its mutant HSV1-sr39tk. ^sup 18^F-FHBG has suitable pharmacokinetics...Zealand White rabbits were divided into equal groups receiving either 14 g/kg cold FHBG...Key Words: PET reporter ...

Effects of Therapy with [^sup 177^Lu-DOTA^sup 0^, Tyr^sup 3^]Octreotate in...

The Journal of Nuclear Medicine;  October 1, 2006 ;     700+ words ......somatostatin analog [^sup 177^Lu-DOTA^sup 0^, Tyr^sup 3^]oetreotate (^sup 177^Lu-octreotate) (DOTA is 1.4.7.10tetraazacyclododecane...neuroendocrine tumors (GEP NETs). An analysis of the effect of ^sup 177^Lu-octreotate treatment on 131 patients of this group...very favorably with ...

Optimized ^sup 124^I PET Dosimetry Protocol for Radioiodine Therapy of...

The Journal of Nuclear Medicine;  June 1, 2008 ;     700+ words ......or high LDpAs (>10 Gy GBq^sup -1^; n = 14). Using the reference...approaches. Results: The effective ^sup 124^I half-life, linear activity-concentrati...the latter 2 per administered ^sup 124^I activity) differed significantly...c^ value of greater than or equal to 0.90 was found, and the ...

Whole-Body PET/CT with ^sup 11^C-Meta-Hydroxyephedrine in Tumors of the...

The Journal of Nuclear Medicine;  October 1, 2006 ;     700+ words ......higher in comparison with ^sup 123^I-MIBG uptake in 26 lesions...soft tissue, 18; bone. 8), equal in 39 lesions (0.48; soft tissue...bone, 9), and lower than ^sup 123^I-MIBG uptake in 16 lesions...detected more tumor lesions than ^sup 123^I-MIBG SPECT/CT. However, tumor-to-background contrast of ...

Subsolidus behavior of niobian rutile from the Písek region, Czech...

Journal of the Czech Geological Society;  January 1, 2007 ;     700+ words ......products include (i) the most common case with dominant (Fe^sup 2+^Nb^sub 2^) Ti^sup -3^ substitution (e.g., Vezn, western Moravia, with exsolved...2000b); (ii) the much less widespread substitution [(Fe, Sc)^sup 3+^Nb] Ti^sub -2^ (Norwegian localities, with exsolved titanian (Fe, Sc)^sup ...

Route of Tracer Administration Does Not Affect Ileal Endogenous Nitrogen...

The Journal of Nutrition;  November 1, 2004 ;     700+ words ......oral administration or continuous i.v. administration of [^sup 15^N]-L-leucine (carotid artery), both at 5 mg/(kg body weight...from a catheter in the external jugular vein. Mean plasma ^sup 15^N-enrichment at d 8-10 was higher (P = 0.0009) after i...administration [0.0356 vs. 0.0379 atom% excess (APE)]. Plasma ...

Kids + planes need not equal disaster

Concord Monitor;  April 20, 2008 ;     535 words ......scarier scenario . . . KIDS on a plane! Just joking, of course (mostly), but kids in airplanes can be a challenge. [sup 2][sup 2][sup 2] The kids: To get the kids' perspective, I interviewed my grandkids Brayden (8) and Chloe (5) and learned quickly...

^sup 18^F-FDG PET/CT, ^sup 99m^Tc-MIBI, and MRI in Evaluation of Patients...

The Journal of Nuclear Medicine;  February 1, 2008 ;     700+ words ......modalities-including whole-body ^sup 18^F-FDG PET/CT, whole-body ^sup 99m^Tc-methoxyisobutylisonitrile (^sup 99m^Tc-MIBI) scintigraphy, and MRI-have been proposed in the...management of MM patients in a noninvasive manner (5-7). ^sup 18^F-FDG PET/CT is a wholebody imaging technique capable ...

PET Imaging of the Dopamine Transporter with ^sup 18^F-FECNT: A Polar...

The Journal of Nuclear Medicine;  March 1, 2006 ;     700+ words ......Carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl)-nortropane (^sup 18^F-FECNT), a PET radioligand for the dopamine transporter...regions of the brain. Methods: Two rats were infused with ^sup 18^F-FECNT and sacrificed at 60 min. Extracts of brain and...human participants and 3 rhesus monkeys were injected ...

Proposed Addendum to Previously Published Fetal Dose Estimate Tables for...

The Journal of Nuclear Medicine;  April 1, 2004 ;     700+ words ......only from activity in maternal organs; such was the case for ^sup 18^F-FDG. A recent publication (3) reported quantitative values for maternal and fetal uptake of ^sup 18^F-FDG in primates and reported estimated values of uptake in fetal brain and heart. In addition, new values for ^sup 18^F-FDG kinetics ...