Article: When statins aren't enough: New trial drug points to better management of coronary heart disease.(Clinical report)

(PHILADELPHIA) u Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and block blood flow. The drug darapladib may offer a way to fight that risk, according to new research led by the University of Pennsylvania School of Medicine (see also University of Pennsylvania School of Medicine ).

Researchers at the Penn and several other international sites have found that the drug may be a useful adjunct to treatment with statin drugs. The new ...

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