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Article: Data on iron overload animal studies detailed by H. Kudo and co-authors.
- Article from:
- Health & Medicine Week
- Article date:
- May 19, 2008
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A new study, 'Effects of colloidal iron overload on renal and hepatic siderosis and the femur in male rats,' is now available. "Genetic hemochromatosis is an iron overload disorder, and osteopenic and osteoporotic. Femoral neck bone mineral density (BMD) appears to fall with rising hepatic iron concentrations," researchers in Tokyo, Japan report (see also
Iron Overload Animal Studies
).
"A critical role for iron in mediating tissue injury is played via hydroxyl radical formation in nephrotoxicity. We investigated the effects of a colloidal iron overload on renal function, organ siderosis, and femoral bone in male rats. Iron overload reduced body growth, and ...