Article: PCa at end of biopsy core a bad sign: extracapsular extension found in nearly 60% of men with tumor cells at the end of a needle core.

DENVER -- The presence of tumor cells at the end of a needle biopsy core obtained near the capsule is an independent indicator of a significantly elevated risk of extracapsular extension, according to data presented here at the annual meeting of the United States and Canada Academy of Pathology.

In a study of 185 men who underwent radical prostatectomies who were available for tumor-stage follow-up, Kirk Ke Lin, MD, director of genitourinary pathology at AmeriPath, Inc., discovered that 50.9% of cases with cancerous cells in the end of the needle core near the capsule had stage pT3a or pT3b prostate cancer compared with just 16.2 % of cases that did not have ...

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