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Article: Onset of action of ciclesonide once daily in the treatment of seasonal allergic rhinitis.(ORIGINAL ARTICLE)(Clinical report)
- Article from:
- Ear, Nose and Throat Journal
- Article date:
- June 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 Vendome Group LLC. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Ciclesonide is an intranasal corticosteroid approved for the treatment of allergic rhinitis. We conducted a randomized, double-blind, parallel-group, placebo-controlled study to evaluate the time to onset of action of ciclesonide 200 lag once daily in 502 adults with seasonal allergic rhinitis of at least 2 years' duration. To trigger immunologic priming, patients underwent between one and five priming sessions with exposure to 3,500 grains/[m.sup.3] ([+ or -] 500) of ragweed pollen in an environmental exposure chamber. The criteria for a successful priming session was a patient-assessed instantaneous total nasal symptom score of at least 6 (of a ...