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Article: Research from Sejong University in life sciences provides new insights.
- Article from:
- Health & Medicine Week
- Article date:
- May 26, 2008
CopyrightCOPYRIGHT 2008 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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According to recent research from Seoul, South Korea, "alpha-Synuclein is a neural protein that comprises the fibrillar core of Lewy bodies, a histologically defining lesion of Parkinson's disease. To investigate the role of each specific residue of the alpha-synuclein molecule in fibril formation, amino acid substitutions were introduced throughout the molecule."
"Incorporation of proline, especially in the region spanning residues 37-89, drastically retarded fibril formation. Substitutions with polar residues showed that the hydrophobicity of the central hydrophobic region is also important in fibrillation regulation. In the N-terminal repeated region, ...
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Article: Researchers at Sejong University release new data ...
Chemicals & Chemistry;
March 27, 2009 ;
577 words
... ... wrote W. Park and colleagues, Sejong University. The researchers concluded: "Their ... additional information, contact D. Lim, Sejong University, Dept. of Chemical, Kunja Dong ... Bioorganic & Medicinal Chemistry, Sejong University. This article was prepared by Chemicals ...
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