Article: TREDAPTIVE(TM) (nicotinic acid /laropiprant) Approved in the European Union: New Lipid-Modifying Therapy to Treat LDL-C, HDL-C and Triglycerides.

WHITEHOUSE STATION, N.J., U.S.A. -- Merck Sharp & Dohme (MSD) announced today that TREDAPTIVE([TM]) (nicotinic acid/laropiprant, MSD) 1 g/20 mg modified-release tablets, a new lipid-modifying therapy for patients with dyslipidemia and primary hypercholesterolemia, has been approved for marketing in the European Union (EU), Iceland and Norway.

TREDAPTIVE combines nicotinic acid (niacin) and laropiprant, a novel flushing pathway inhibitor. In clinical studies involving more than 4,700 patients, TREDAPTIVE reduced LDL-cholesterol (LDL-C, or "bad" cholesterol) levels, raised HDL-cholesterol (HDL-C, or "good" cholesterol) levels and decreased triglycerides (a type of ...

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