Article: A reversible lesion of the corpus callosum splenium with adult influenza-associated encephalitis/encephalopathy: a case report.(Case report)(Case study)

Authors: En Kimura (corresponding author) [1]; Sadahisa Okamoto [1]; Yuji Uchida [1]; Tomoo Hirahara [1]; Tokunori Ikeda [1]; Teruyuki Hirano [1]; Makoto Uchino [1]

Introduction

Influenza virus-associated encephalitis/encephalopathy (IAEE) [1, 2, 3, 4] is known to have a poor prognosis in childhood, especially in children under the age of 5 years. An acute necrotizing encephalopathy, Reye's syndrome, hemorrhagic shock and encephalopathy are the most feared and often fatal complications in IAEE [5, 6]. Although there has been a great improvement in therapeutic approaches, the rates of mortality (31.8%) and disability (27.7%) are still quite high. ...

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