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Article: Lupus patients have extremely low levels of vitamin D.(Rheumatology)
- Article from:
- Internal Medicine News
- Article date:
- June 15, 2008
CopyrightCOPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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NEW YORK -- Patients with lupus have "dramatically" low serum levels of the biologically active form of vitamin D, a deficiency that may contribute to the pathological processes involved in their disease, Dr. Peter E. Lipsky said at a rhematology meeting sponsored by New York University.
Previous work has shown that 1,25 (OH)[sub.2][D.sub.3] is an important regulator of lymphocyte and dendritic cell function, and many patients with autoimmune diseases are deficient in this vitamin.
To test the hypothesis that vitamin D deficiency is contributing to the lymphocyete overactivity characteristic of lupus, investigators measured serum levels of 1, 25 ...
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