Article: Transient and reversible focal lesion involving the splenium of the corpus callosum in a person with epilepsy.(Images in Neurology)(Case study)

Byline: Nitin. Parikh, Makarand. Kulkarni

Case Report

A 40-year-old man with epilepsy was admitted with relapse of generalized tonic-clonic seizures following inadvertent discontinuation of phenytoin that he had been taking regularly. His neurological examination and previous brain magnetic resonance imaging (MRI) were normal. A repeat MRI (1.5-Tesla superconducting magnet, Symphony, Siemens, Germany) of the brain, using axial T1-weighted spin-echo (500 TR / 11 TE), axial and sagittal T2-weighted turbo spin-echo (6000 TR / 90 TE), axial FLAIR, and diffusion-weighted and ADC sequences, revealed a solitary well-defined ovoid lesion in the splenium of the ...

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