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Article: New findings in colon cancer risk factors described from University of Newcastle, Hunter Medical Research Institute.
- Article from:
- Cancer Weekly
- Article date:
- July 29, 2008
CopyrightCOPYRIGHT 2008 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Investigators publish new data in the report 'The -149C>T SNP within the DeltaDNMT3B gene, is not associated with early disease onset in hereditary non-polyposis colorectal cancer.' "Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited syndrome caused by germline mutations in mismatch repair (MMR) genes. HNPCC patients have a lifetime risk of 80% of developing colorectal cancer (CRC); however the likely age of onset is difficult to predict," researchers in Australia report (see also Colon Cancer Risk Factors).
"A single C>T polymorphism located within the promoter region of the DeltaDNMT3B gene has recently been reported to be ...
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