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Article: New findings reported from M. Hornyak and co-authors describe advances in restless legs syndrome.
- Article from:
- Biotech Week
- Article date:
- July 30, 2008
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According to recent research from Freiburg, Germany, "Circadian symptom manifestation in the evening and night is one of the main characteristics of restless legs syndrome (RLS). Although the inverse temporal course of corticosteroid rhythm and RLS symptom severity is obvious, this relationship has yet to be studied."
"We investigated the effect of late-evening application of exogenous cortisol (hydrocortisone) on sensory leg discomfort (SLD), one of the main complaints of patients with RLS. Ten untreated patients with idiopathic RLS participated in the study. Change of SLD was rated on a visual analogue scale during the 60 minutes resting period of the so-called ...