Article: Reports from City of Hope National Medical Center advance knowledge in apoptosis cell biology.(Report)

Research findings, 'Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo,' are discussed in a new report. "The farnesoid X receptor (FXR) is a key metabolic regulator in the liver by maintaining the homeostasis of liver metabolites. Recent findings suggest that FXR may have a much broader function in liver physiology and pathology," investigators in the United States report (see also Apoptosis Cell Biology).

"In the present work, we identify a novel role of FXR in protecting liver cell from apoptosis induced by nutritional withdrawal including serum deprivation in vitro or starvation in vivo. Two FXR ...

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