Article: Research from Ullevaal University in Addison disease genetics provides new insights.

A new study, 'Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease,' is now available. According to a study from Oslo, Norway, "The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently identified as an important genetic susceptibility factor in several autoimmune diseases. The increased risk has been broadly explained by the 1858T-allele (rs2476601)."

"As two smaller studies on Addison's disease (AD) have shown diverging results, we aimed to elucidate the predisposing effect of the single-nucleotide polymorphism (SNP) 1858CT in a larger population of AD patients, especially focusing on the AD patients with ...

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