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Article: New findings from University of Salamanca describe advances in physiology.
- Article from:
- Biotech Week
- Article date:
- August 27, 2008
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Fresh data on physiology are presented in the report 'Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes.' According to recent research published in the American Journal of Physiology - Gastrointestinal and Liver Physiology, "Bile acids (BAs) are natural ligands of nuclear receptors, in particular farnesoid X receptor (FXR). Whether, in addition to protein-mediated cytosolic-nuclear BA translocation, other mechanisms are involved in the access of BAs to nuclear FXR was investigated."
"When rat hepatocytes were incubated with radiolabeled taurocholic acid, taurodeoxycholic acid, taurochenodeoxycholic acid, and ...