Article: Study findings from E.P. Murchison et al provide new insights into genome research.

"Small RNA pathways play evolutionarily conserved roles in gene regulation and defense from parasitic nucleic acids. The character and expression patterns of small RNAs show conservation throughout animal lineages, but specific animal clades also show variations on these recurring themes, including species-specific small RNAs," researchers in the United States report (see also Genome Research).

"The monotremes, with only platypus and four species of echiDNA as extant members, represent the basal branch of the mammalian lineage. Here, we examine the small RNA pathways of monotremes by deep sequencing of six platypus and echiDNA tissues. We find that highly ...

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