Article: Reports from Nancy University advance knowledge in life sciences.

According to a study from Nancy, France, "Moderate consumption of red wine is associated with a lower incidence of cardiovascular disease. Red wine polyphenols (RWP) have been proposed to be beneficial, but there is lack of evidence concerning the cerebrovascular effects of RWP."

"We studied the effect of local administration of a RWP extract (10(-2) mg/mL) on the diameter of rat cerebral arterioles using an open cranial window technique in vivo. We measured cerebral arteriolar diameter and systemic blood pressure. Cerebral arterioles reacted concentration-dependently to adenosine diphosphate [ADP, dilatation EC50 5.3 X 10(-5) M (95% confidence interval: 3.1 to ...

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