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Article: Researchers from Virginia Polytechnic Institute and State University, Center for Molecular Medicine and Infectious Diseases report on findings in genetics & genomics.
- Article from:
- Biotech Week
- Article date:
- August 20, 2008
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Current study results from the report, 'Construction of a high-efficiency shuttle vector for Histophilus somni,' have been published. "The genetic manipulation of Histophilus somni is limited due to its high-fidelity restriction-modification system. The broad host-range shuttle plasmid pLS88 is capable of transforming some strains of H. somni, but is an inefficient vector," scientists writing in the Journal of Microbiological Methods report (see also Genetics & Genomics).
"We have constructed an improved version of pLS88, pNS3K, that transforms H. somni strain 2336 100-fold more efficiently than its predecessor. The transformation efficiency was further increased ...