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Article: Accelerated Aging of Immune Cells Linked to Exhaustion of Immune Response in Patients with AIDS; Telomere Research Suggests Role of Cell Senescence in HIV Disease Process.
- Article from:
- Business Wire
- Article date:
- June 27, 1996
CopyrightCOPYRIGHT 1996 Business Wire. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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MENLO PARK, Calif.--(BUSINESS WIRE)--June 27, 1996--Research focused on a key marker of cell replication demonstrates that the immune cells of HIV-infected patients age at an accelerated rate, suggesting an explanation for the eventual breakdown of the immune response in AIDS.
The findings, published today in the journal AIDS by scientists from Geron Corporation and UCLA School of Medicine, are the first to suggest a role for cell aging, or senescence, in the HIV disease process.
In this study, the researchers examined the immune cells of patients with late-stage HIV and found that these cells had apparently aged to a level similar to those of a normal ...