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Article: NewCo News Wintherix Uses Pfizer Library to Find Wnt Inhibitors for Cancer.
- Article from:
- BIOWORLD Today
- Article date:
- September 4, 2008
- Author:
CopyrightCOPYRIGHT 2008 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Byline: Trista Morrison, Staff Writer
Founded in January, San Diego-based Wintherix LLC is knee-deep in drug screening efforts that it hopes will result in small-molecule Wnt inhibitors for the treatment of cancer.
The Wnt pathway is activated in cancers of the colon, breast, prostate, lung and blood. According to Wintherix Chief Scientific Officer John Hood, more than 500,000 new cases of cancer each year involve Wnt activation.
Wnt also is believed to be required for self-renewal of cancer stem cells, Hood said.
Research has indicated that despite oncologists' best efforts to attack tumors with surgery, chemotherapy, radiation and a ...