Article: Once-weekly exenatide lowers glycemia, weight.(News)

SAN FRANCISCO--An investigational once-weekly formulation of exenatide resulted in superior improvements in glucose control at 30 weeks, compared with the current twice-daily version, and clicited sustained glycemic control and weight loss at 1 year in patients with type 2 diabetes.

The phase III data were presented in two separate sessions at the annual scientific sessions of the American Diabetes Association. The twice-daily injectable in-cretin mimetic is comarketed as Byetta by Amylin Pharmaceuticals Inc., Eli Lilly & Co., and Alkermes Inc. An application for approval of the long-acting release formulation was filed with the Food and Drug Administration in ...

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