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Article: Data on obstetrics and gynecology detailed by A.T. Moynihan and co-authors.(Report)
- Article from:
- Women's Health Weekly
- Article date:
- September 4, 2008
CopyrightCOPYRIGHT 2008 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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According to recent research published in the American Journal of Obstetrics and Gynecology, "This study was undertaken to investigate the effects of 3 histone deacetylase inhibitors on human uterine contractility. Biopsy specimens of human myometrium were obtained at elective cesarean section (n = 18)."
"Dissected myometrial strips suspended under isometric conditions, undergoing spontaneous, and oxytocin-induced contractions, were subjected to cumulative additions of 3 histone deacetylase inhibitors: trichostatin A, suberic bishydroxamate (1 nmol/L-10 mu mol/L) and valproic acid (100 nmol/L - 1 mmol/L). Control experiments were run simultaneously. Integrals of ...