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Article: New monoclonal antibodies research from K. Mnasria and co-researchers described.(Report)
- Article from:
- Blood Weekly
- Article date:
- September 4, 2008
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Researchers detail in 'Anti-CD25 antibodies affect cytokine synthesis pattern of human dendritic cells and decrease their ability to prime allogeneic CD4+ T cells,' new data in monoclonal antibodies. "Anti-CD25 monoclonal antibodies are widely used in clinical transplantation to prevent acute allograft rejection. Although their effects on T lymphocytes have been extensively studied, their impact on human dendritic cells (DC) has never been reported," scientists writing in the Journal of Leukocyte Biology report (see also Monoclonal Antibodies).
"Furthermore, the role of the IL-2 in DC functions has not yet been fully elucidated. In this study, we confirm that the ...