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Article: Data from Heidelberg University, Biochemistry Center advance knowledge in life sciences.
- Article from:
- Science Letter
- Article date:
- September 2, 2008
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Investigators publish new data in the report 'Rerouting of fibroblast growth factor 2 to the classical secretory pathway results in post-translational modifications that block binding to heparan sulfate proteoglycans.' "FGF-2 is a proangiogenic growth factor secreted by unconventional means. It is unknown why FGF-2 takes an ER/Golgi-independent secretory route," researchers in Germany report (see also Life Sciences).
"We find that secretion of FGF-2 via the ER/Golgi system causes post-translational modifications that prevent binding to heparan sulfate proteoglycans (HSPGs), an interaction that is critically important for both FGF-2 storage and signal ...
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Article: Research on life sciences described by scientists ...
Science Letter;
October 20, 2009 ;
700+ words
... ... Germany report (see also Life Sciences). "On the extracellular side ... C. Torrado and colleagues, Heidelberg University, Biochemistry Center. The ... Keywords: Germany, Heidelberg, Life Sciences, Biochemistry. This article ...
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