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Article: Study data from Kaohsiung Medical University update knowledge of nasal polyps.
- Article from:
- Biotech Week
- Article date:
- September 24, 2008
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In this recently published study, investigators in Kaohsiung, Taiwan conducted a study "To systematically investigate the role of matrix metalloprotemase-2 (MMP2) tagging single nucleotide polymorphisms (SNPs) and promoter functional polyniorphism in the development of nasal polyps in a Chinese population in Taiwan. We conducted a case-control study in 136 cases of chronic rhinosinusitis with bilateral nasal polyps and 136 controls."
"Seventeen SNPs were selected, including 16 tagging SNPs and I promoter functional SNP. The genotypes were determined by TaqMan technology. Hardy-Weinberg equilibrium was tested for each SNP, and genetic effects were evaluated ...