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Article: Research conducted at Shandong University, Department of Otorhinolaryngology has updated our knowledge about nasal polyps.
- Article from:
- Biotech Week
- Article date:
- September 24, 2008
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Researchers detail in 'Superantigens and the expression of T-cell receptor repertoire in chronic rhinosinusitis with nasal polyps,' new data in nasal polyps. "Staphylococcal exotoxins (SEs), acting as superantigens, activate the beta variable chains of T-cell receptors (TCRVbeta) with subsequent massive proliferation and corresponding excursion of gene spectra, thereby contributing to the etiology of chronic rhinosinusitis with nasal polyps (CRSwNP). To demonstrate the presence of SEs in sinonasal mucosa, and determine the effect of superantigens on the T cells expressing the target of superantigen, i.e," investigators in Jinan, People's Republic of China report (see also ...