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Article: Reports outline bone marrow transplant research from R. Gupta and colleagues.
- Article from:
- Blood Weekly
- Article date:
- September 25, 2008
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"Studies have shown various cardiotoxic effects of high-dose chemotherapy (HDC) used for conditioning before autologous bone marrow transplant (ABMT) including arrhythmias but only a transient small decrease in left ventricle ejection fraction (LVEF)," scientists writing in the Echocardiography - a Journal of Cardiovascular Ultrasound and Allied Techniques report (see also Bone Marrow Transplant).
"To our knowledge, an acute dramatic decrease in LVEF after HDC preconditioning has never been reported. We report a patient presenting with an acutely symptomatic heart failure within 2 weeks of receiving HDC conditioning for ABMT with an LVEF drop from normal to
The ...