Article: Serum anticholinergic activity and cerebral cholinergic dysfunction: An EEG study in frail elderly with and without delirium.(Research article)(electroencephalography)(Report)

Authors: Christine Thomas (corresponding author) [1,2]; Ute Hestermann [3]; Juergen Kopitz [4]; Konstanze Plaschke [5]; Peter Oster [3]; Martin Driessen [2]; Christoph Mundt [1]; Matthias Weisbrod [1]

Background

Additive long lasting anticholinergic side effects of commonly prescribed drugs have recently gained special interest in neuro-geriatric medicine. They are considered one of the main reasons for cognitive decline [1] and delirium in the elderly. Although delirium is a common cause of morbidity and even mortality in the frail elderly and by this has an enormous impact on health economy as well as on individual quality of life, it remains ...

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