Article: Antihistamine may slow pace of cognitive decline in Alzheimer's.(Geriatric Psychiatry)

CHICAGO -- An off-the-market antihistamine previously shown to slow cognitive decline over 1 year in Alzheimer's patients continued to preserve cognition and memory during a 6-month open-label extension trial.

The drug, dimebon, also stabilized cognition in patients who started on it after taking placebo during the original trial, Dr. Jeffrey Cummings said at the International Conference on Alzheimer's Disease.

"People initially treated with placebo and then crossed over to dimebon did not show the same level of benefit as those people who took dimebon for 18 months after starting the [initial] study," said Dr. Cummings, the Augustus S. Rose Professor ...

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