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Article: Research from R. Maurya and co-authors reveals new findings on diabetes.
- Article from:
- Diabetes Week
- Article date:
- October 13, 2008
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"The protein tyrosine phosphatases (PTPase) are a group of regulatory enzymes that are critically important to a wide variety of cellular functions. PTPase 1B has recently been implicated in the pathogenesis of diabetes, neuronal disease, and autoimmune diseases," researchers in Lucknow, India report (see also Diabetes).
"A number of these PTPase that act as negative regulators of the insulin signaling cascade have been identified as novel targets for the therapeutic enhancement of insulin action in insulin-resistant disease states like type II diabetes. Therefore, in the present work we describes a study of the synthesis and structure-activity relationship ...